Active Research Studies

At the core of the Laboratory for Translational Neurorecovery is a hypothesis-driven and quantitative approach to clinical research informed by both fundamental human neuroscience and neural engineering.

Stroke Motor Rehabilitation and Recovery Study (SMaHRT)

The MGH Stroke Motor Rehabilitation and Recovery Study (SMaHRT) is an observational, natural history, and interdisciplinary research study of motor recovery after stroke. We collect rehabilitation-focused outcomes starting during the acute stroke hospitalization at Massachusetts General Hospital and continuing over time across the post-acute care continuum. We are closely integrate with the MGH Neurorecovery Clinic. We apply quantitative methods to analyzing outcomes data informed by neuro- and rehab- sciences.

Systems Neuroscience Subserving Stroke Motor Recovery

We apply quantitative analysis of data from neuroimaging, EEG, and Transcranial Magnetic Stimulation (TMS) to understand how neural structure and function contribute to stroke motor recovery. This work is in close collaboration with the Laboratory for Restorative Neurotechnology and the Brain Recovery Lab. To date, work in our lab has established novel and automated methods for quantifying injury to key brain structures responsible for arm motor recovery after stroke.

Designing Next Generation Neurotechnologies for Neurorehabiliation

We are working with a multidisciplinary team to design a novel EEG-driven Brain-Computer Interface Arm Orthosis System to maximize arm motor neurorehabilitation. We inform our engineering with neuroscientific insights from the natural history of stroke recovery as well as cutting-edge neural decoding strategies. This work is in close collaboration with the Laboratory for Restorative Neurotechnology (BrainGate).

Portable Neurotechnology for Post-Stroke Motor Rehabilitation

The MGH PoRtable method Of MOTor rEhabilitation using functional Near-Infrared Spectroscopy-based brain-computer-interface to augment post-stroke
recovery (PROMOTE) Study investigates how a novel, portable functional Near-Infrared Spectroscopy (fNIRS) based brain computer interface (BCI) system may be utilized in the home to promote upper-extremity recovery in chronic stroke survivors. Participants undergo a 5-week telehealth rehabilitative program with pre- and post- assessment.