Performance and Participation Outcomes for Individuals With Neurological Conditions

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Authors: Naomi Josman, Lisa Tabor Connor, David J Lin    Abstract: The goal of this current theme issue was to foster original research papers in neuroscience and rehabilitation science that may serve to address the existing disconnect between disciplines. This platform offered an opportunity for a meaningful exchange of ideas, findings, and practices toward ultimately promoting …

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Inflatable Soft Wearable Robot for Reducing Therapist Fatigue During Upper Extremity Rehabilitation

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Authors: Ciarán O’Neill, Tommaso Proietti, Kristin Nuckols, Megan E. Clarke, Cameron J. Hohimer, Alison Cloutier, David J. Lin, Conor J. Walsh  Abstract: Intense therapy is a key factor to improve rehabilitation outcomes. However, when performing rehabilitative stretching with the upper limb of stroke survivors, therapist fatigue is often the limiting factor for the number of repetitions per session. …

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Interdisciplinary Stroke Recovery Research: The Perspective of Occupational Therapists in Acute Care

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Authors: Jessica Ranford, Jessica Asiello, Alison Cloutier, Kimberly Cortina, Helena Thorne, Kimberly S. Erler, Natasha Frazier, Caitlin Sadlak, Abigail Rude, and David J. Lin Abstract: As acute stroke treatments advance, more people survive the initial stroke event and live with long-term neurological impairments that impact functional outcomes and quality of life. In accordance with International Classification of Functioning …

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New Directions in Treatments Targeting Stroke Recovery

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Authors: David J. Lin, Seth P. Finklestein, Steven C. Cramer Stroke is the leading cause of neurological disability in the United States and worldwide. Remarkable advances have been made over the past 20 years in acute vascular treatments to reduce infarct size and improve neurological outcome. Substantially, less progress has been made in treatments to enhance …

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Corticospinal Tract Injury Estimated From Acute Stroke Imaging Predicts Upper Extremity Motor Recovery After Stroke

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Authors: David J. Lin, Alison M. Cloutier, Kimberly S. Erler, Jessica M. Cassidy, Samuel B. Snider, Jessica Ranford, Kristin Parlman, Fabio Giatsidis, James F. Burke, Lee H. Schwamm, Seth P. Finklestein, Leigh R. Hochberg, Steven C. Cramer Abstract: Background and Purpose — Injury to the corticospinal tract (CST) has been shown to have a major effect on upper …

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Combining Fluoxetine and rTMS in Post stroke Motor Recovery

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Authors: Bonin Pinto C., Morales-Quezada .L, de Toledo Piza P.V., Zeng D., Saleh Vélez F.G., Ferreira I.S., Lucena P.H., Duarte D., Lopes F., El-Hagrassy M.M., Rizzo L.V., Camargo E.C., Lin D.J., Mazwi N., Wang Q.M., Black-Schaffer R., Fregni F. Abstract: Background. Although recent evidence has shown a new role of fluoxetine in motor rehabilitation, results are mixed. We …

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Stroke Tank Winner: Congratulations to Dr. David J. Lin

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Congratulations to Dr. David Lin for presenting a winning pitch at Stroke Tank. The winnings will provide funding to start to scale our MGH SMaHRT (Stroke Motor reHabilitation and Recovery sTudy) to the hospitals in the NECC network.  

Changes in input strength and number are driven by distinct mechanisms at the retinogeniculate synap

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Authors: David J. Lin, Erin Kang, Chinfei Chen Abstract: Recent studies have demonstrated that vision influences the functional remodeling of the mouse retinogeniculate synapse, the connection between retinal ganglion cells and thalamic relay neurons in the dorsal lateral geniculate nucleus (LGN). Initially, each relay neuron receives a large number of weak retinal inputs. Over a 2- to …

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